Compound Summary
Compound Information
125941-87-9
Compound Name: | 125941-87-9 |
Compound CID: | 11957535 |
Synonyms: | 125941-87-9 SCH 23390 HYDROCHLORIDE R(+)-SCH-23390 hydrochloride SCH-23390 hydrochloride UNII-4S8T3E2F4Z More... |
Iupac Name: | (5R)-8-chloro-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol;hydrochloride |
InChI: | InChI=1S/C17H18ClNO.ClH/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12;/h2-6,9-10,15,20H,7-8,11H2,1H3;1H/t15-;/m1./s1 |
InChIKey: | OYCAEWMSOPMASE-XFULWGLBSA-N |
Canonical Smiles: | CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Cl.Cl |
Isomeric Smiles: | CN1CCC2=CC(=C(C=C2[C@H](C1)C3=CC=CC=C3)O)Cl.Cl |
Molecular Weight: | 324.2 |
Molecular Formula: | C17H19Cl2NO |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
125941-87-9
Molecular Weight: | 324.2 |
Molecular Formula: | C17H19Cl2NO |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 21 |
Complexity: | 318 |
Synonyms
125941-87-9
| 125941-87-9 | 125941-87-9 |
|---|---|
125941-87-9 |
SCH 23390 HYDROCHLORIDE |
R(+)-SCH-23390 hydrochloride |
SCH-23390 hydrochloride |
UNII-4S8T3E2F4Z |
(R)-(+)-Sch 23390 Hydrochloride |
SCH23390 HCl |
4S8T3E2F4Z |
R(+)SCH23390 hydrochloride |
SCH 23390 |
R-(+)-SCH23390 hydrochloride |
125941-87-9 (HCl) |
SCH-23390 (hydrochloride) |
(R)-2,3,4,5-Tetrahydro-8-chloro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrochloride |
(R)-8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzodazepin-7-ol hydrochloride |
(R)-(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride |
SMR000326935 |
SCH23390 |
87134-87-0 |
(5R)-8-Chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3-benzazepin-7-ol hydrochloride |
EU-0100456 |
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-, hydrochloride, (5R)- |
MLS000759024 |
MLS000860077 |
MLS001424251 |
SCH-23390 HCl |
SCHEMBL1774187 |
CHEMBL1256645 |
DTXSID9074484 |
AOB5687 |
R(+)-7-Chloro-8-hydroxy-3- |
BCP20717 |
R(+)-SCH-23390 HCl |
Tox21_500456 |
HY-19545A |
AKOS024458699 |
CCG-101196 |
CS-6480 |
LP00456 |
NC00446 |
NCGC00261141-01 |
AS-16912 |
B6506 |
SR-01000075380 |
SR-01000597829 |
J-005303 |
SR-01000075380-1 |
SR-01000597829-1 |
Q27260427 |
R(+)-SCH-23390 hydrochloride, >=98% (HPLC), solid |
methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride |
(5R)-8-chloro-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol;hydrochloride |
1H-3-BENZAZEPIN-7-OL, 8-CHLORO-2,3,4,5-TETRAHYDRO-3-METHYL-5-PHENYL-, HCL (1:1), (5R)- |
Experimental Data
125941-87-9
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -1 | NS | N2 | 24134630 | Inactive | ||||||
| Caenorhabditis elegans | 10 | umol/L | 16.18 | 15.94 | -1.466 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100 | umol/L | 15.99 | 16.8 | 5.056 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
125941-87-9
Statistics Data
125941-87-9
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 5.056 | 2 | 3 |
Statistics Data Visualization
125941-87-9
