Compound Summary
Compound Information
Amitriptyline hydrochloride
Compound Name: | Amitriptyline hydrochloride |
Compound CID: | 11065 |
Synonyms: | Amitriptyline hydrochloride 549-18-8 Amitriptyline HCl Annoyltin Tryptizol More... |
Iupac Name: | N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine;hydrochloride |
InChI: | InChI=1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H |
InChIKey: | KFYRPLNVJVHZGT-UHFFFAOYSA-N |
Canonical Smiles: | CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl |
Isomeric Smiles: | CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl |
Molecular Weight: | 313.9 |
Molecular Formula: | C20H24ClN |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Amitriptyline hydrochloride
Molecular Weight: | 313.9 |
Molecular Formula: | C20H24ClN |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 1 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 22 |
Complexity: | 331 |
Synonyms
Amitriptyline hydrochloride
| Amitriptyline hydrochloride | Amitriptyline hydrochloride |
|---|---|
Amitriptyline hydrochloride |
549-18-8 |
Amitriptyline HCl |
Annoyltin |
Tryptizol |
Domical |
Lentizol |
Saroten |
Endep |
Elavil hydrochloride |
Amineurin |
Amitrip |
Anapsique |
Laroxyl |
Syneudon |
Tryptine |
Amavil |
Ami-Anelun |
Apo-Amitriptyline |
Daprimen |
Elatrolet |
Maxivalet |
Miketorin |
Mitaptyline |
Rantoron |
Sarotena |
Trepiline |
Triptizol |
Trytomer |
Vanatrip |
Yamanouchi |
Amilit |
Amiplin |
Amiprin |
Amitid |
Amyline |
Amyzol |
Belpax |
Elatrol |
Enafon |
Etrafon |
Etravil |
Kyliran |
Larozyl |
Levate |
Pinsanu |
Pinsaun |
Teperin |
Triavil |
Tridep |
Tripta |
Trynol |
Damilen hydrochloride |
Amitriptyline chloride |
Saroten Retard |
Tryptizol retard |
Limbitrol DS |
Tryptacap hydrochloride |
ADT-Zimaia |
Oasil-M |
Amitril |
Redomex |
Proheptadien monohydrochloride |
Amitriptyline (hydrochloride) |
sk-Amitriptyline chloride |
Limbitrol |
Sarotex |
CCRIS 7092 |
UNII-26LUD4JO9K |
NIH 10794 |
Amitryptiline hydrochloride |
MFCD00012537 |
Amitryptylline hydrochloride |
C20H24ClN |
26LUD4JO9K |
Annolytin |
MLS000028437 |
Novoprotect |
component of Etrafon |
component of Triavil |
5-(3-(Dimethylamino)propylidene) dibenzosuberane HCl |
3-(10,11-dihydro-5H-dibenzoa,d7annulen-5-ylidene)-N,N-dimethylpropan-1-amine hydrochloride |
NSC-104210 |
Novotriptyn |
Nornaln |
SMR000058368 |
549-18-8 (HCL) |
Amitryptyline hydrochloride |
5-(3-Dimethylaminopropylidene)dibenzo(a,d)(1,4)cycloheptadiene hydrochloride |
DSSTox_CID_13187 |
DSSTox_RID_79055 |
DSSTox_GSID_33187 |
1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride |
1-propanamine, 3-(10,11-dihydro-5H-dibenzoa,dcyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride |
1-Propanamine, 3-(10,11-dihydro-5H-dibenzoa,dcyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride (1:1) |
3-(10,11-Dihydro-5H-dibenzoa,d7annulen-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride |
NSC169910 |
WLN: L C676 BY&T&J BU3N1&1 &GH |
SR-01000003046 |
NCGC00015095-09 |
CAS-549-18-8 |
EINECS 208-964-6 |
NSC 104210 |
Amilent |
Sylvemid |
Amicen |
Euplit |
Uxen |
5-(3-Dimethylaminopropylidene)dibenzoa,4cycloheptadiene hydrochloride |
5-3-(Dimethylamino)propylidenedibenzoa,4cycloheptadiene hydrochloride |
1-Propanamine,11-dihydro-5H-dibenzoa,dcyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride |
5-(3-Dimethylaminopropylidene)dibenzoa,d1,4cycloheptadiene hydrochloride |
5H-Dibenzoa,.gamma.-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride |
5H-Dibenzoa,.gamma.-propylamine, 10,11-dihydro-N,N-dimethyl-,hydrochloride |
Prestwick_20 |
1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-, hydrochloride (1:1) |
3-(5,6-dihydrodibenzo2,1-b:1,2-e7annulen-11-ylidene)-N,N-dimethylpropan-1-amine;hydrochloride |
DRG-0169 |
Elavil (TN) |
Amitriptyline hydrochloride USP:JAN |
CPD000058368 |
Opera_ID_618 |
Nortriptyline Impurity F |
C20H23N.HCl |
SCHEMBL41079 |
10,11-Dihydro-N,N-dimethyl-5H-dibenzo(a,d)cycloheptene-delta(sup 5,gamma)-propylamine hydrochloride |
MLS001055393 |
MLS001074176 |
MLS002222152 |
SPECTRUM1500117 |
REGID_for_CID_11065 |
CHEBI:2667 |
CHEMBL1200964 |
DTXSID9033187 |
HY-B0527A |
Amitriptyline Hydrochloride ,(S) |
Amitriptyline hydrochloride, 99% |
HMS1568O09 |
HMS1920C13 |
Pharmakon1600-01500117 |
BCP31573 |
Amitriptyline-13C3 Hydrochloride |
Tox21_113122 |
Tox21_201278 |
Tox21_303612 |
Tox21_500112 |
CCG-38919 |
NSC104210 |
NSC755869 |
s3183 |
AKOS015994716 |
Tox21_113122_1 |
KS-1291 |
LP00112 |
NC00497 |
NSC-169910 |
NSC-755869 |
Amitriptyline hydrochloride (JP17/USP) |
Amitriptyline;Amitriptyline hydrochloride |
NCGC00015095-15 |
NCGC00024433-03 |
NCGC00024433-05 |
NCGC00093609-01 |
NCGC00093609-02 |
NCGC00093609-03 |
NCGC00093609-04 |
NCGC00093609-05 |
NCGC00257393-01 |
NCGC00258830-01 |
NCGC00260797-01 |
5H-Dibenzo(a,d)cycloheptene-delta(sup 5),gamma-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride |
BA164159 |
H905 |
N,N-dimethyl-3-(2-tricyclo9.4.0.03,8pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine;hydrochloride |
Amitriptyline HCl;Nortriptyline Impurity F |
AB0013348 |
A0908 |
EU-0100112 |
FT-0662108 |
FT-0662109 |
SW196337-3 |
A 8404 |
A16404 |
D00809 |
D81789 |
J10484 |
A854879 |
Amitriptyline hydrochloride, >=98% (TLC), powder |
SR-01000003046-2 |
SR-01000003046-6 |
W-105596 |
Q27254112 |
F0001-1443 |
Amitriptyline hydrochloride 100 microg/mL in Acetonitrile |
5-3-(Dimethylamino)propylidenedibenzosuberane hydrochloride |
Amitriptyline Hydrochloride 1.0 mg/ml in Methanol (as free base) |
Amitriptyline hydrochloride, drug standard, 1.0 mg/mL in methanol |
Amitriptyline hydrochloride, British Pharmacopoeia (BP) Reference Standard |
Amitriptyline hydrochloride, European Pharmacopoeia (EP) Reference Standard |
Amitriptyline hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material |
Amitriptyline hydrochloride, United States Pharmacopeia (USP) Reference Standard |
10,11-Dihydro-N,N-dimethyl-5H-dibenzoa,dcycloheptene-Delta5,gamma-propylamine hydrochloride |
3-(10,11-Dihydro-5H-dibenzoa,dcyc lohepten-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride |
3-(10,11-Dihydro-5H-dibenzoa,dcyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine hydrochloride |
5H-Dibenzo(a,d)cycloheptene-delta5,gamma-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride (8CI) |
5H-Dibenzoa,dcycloheptene-Delta(sup5),gamma-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride |
5H-Dibenzoa,dcycloheptene-Delta5,gamma-propylamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride (6CI,8CI) |
Amitriptyline hydrochloride solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material |
N,N-Dimethyl-3-(2-tricyclo9.4.0.03,8pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine;hydron;chloride |
Experimental Data
Amitriptyline hydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 20 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Amitriptyline hydrochloride
Statistics Data
Amitriptyline hydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 20 | 1 | 1 |
Statistics Data Visualization
Amitriptyline hydrochloride
