Compound Summary
Compound Information
U-69593
Compound Name: | U-69593 |
Compound CID: | 105104 |
Synonyms: | U-69593 96744-75-1 U69593 U 69593 UNII-J5S4K6TKTG More... |
Iupac Name: | N-methyl-2-phenyl-N-[(5R,7S,8S)-7-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-8-yl]acetamide |
InChI: | InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)19-10-12-22(11-7-15-26-22)17-20(19)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22-/m0/s1 |
InChIKey: | PGZRDDYTKFZSFR-ONTIZHBOSA-N |
Canonical Smiles: | CN(C1CCC2(CCCO2)CC1N3CCCC3)C(=O)CC4=CC=CC=C4 |
Isomeric Smiles: | CN([C@H]1CC[C@@]2(CCCO2)C[C@@H]1N3CCCC3)C(=O)CC4=CC=CC=C4 |
Molecular Weight: | 356.5 |
Molecular Formula: | C22H32N2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
U-69593
Molecular Weight: | 356.5 |
Molecular Formula: | C22H32N2O2 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 26 |
Complexity: | 485 |
Synonyms
U-69593
| U-69593 | U-69593 |
|---|---|
U-69593 |
96744-75-1 |
U69593 |
U 69593 |
UNII-J5S4K6TKTG |
U 69,593 |
J5S4K6TKTG |
N-Methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4,5)dec-8-yl)benzeneacetamide |
n-methyl-2-phenyl-n-(5r,7s,8s)-7-(pyrrolidin-1-yl)-1-oxaspiro4.5dec-8-ylacetamide |
N-methyl-2-phenyl-N-(5R,7S,8S)-7-pyrrolidin-1-yl-1-oxaspiro4.5decan-8-ylacetamide |
3HU69593 |
CHEBI:73357 |
Benzeneacetamide, N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4.5)dec-8-yl)-, (5alpha,7alpha,8beta)-(-)- |
NCGC00163179-01 |
DSSTox_CID_26326 |
DSSTox_RID_81542 |
N-methyl-N-((5R,7S,8S)-7-(1-pyrrolidinyl)-1-oxaspiro(4.5)dec-8-yl)-benzeneacetamide |
DSSTox_GSID_46326 |
U69,593 |
(+)-N-methyl-2-phenyl-N-(5R,7S,8S)-7-pyrrolidin-1-yl-1-oxaspiro4.5decan-8-ylacetamide |
Benzeneacetamide, N-methyl-N-((5R,7S,8S)-7-(1-pyrrolidinyl)-1-oxaspiro(4.5)dec-8-yl)- |
(+)-(5alpha,7alpha,8beta)-N-Methyl-N-7-(1-pyrrolidinyl)-1-oxaspiro4.5dec-8-yl-benzeneacetamide |
(5alpha,7alpha,8beta)-(-)-N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4.5)dec-8-yl)-benzeneacetamide |
CAS-96744-75-1 |
benzeneacetamide, N-methyl-N-(5R,7S,8S)-7-(1-pyrrolidinyl)-1-oxaspiro4.5dec-8-yl- |
N-methyl-2-phenyl-N-((5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro4.5decan-8-yl)acetamide |
N-methyl-2-phenyl-N-(5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro4.5decan-8-ylacetamide |
PDSP2_001518 |
3H-U69593 |
U-69593, solid |
SCHEMBL726034 |
U-69,593 |
CHEMBL440765 |
GTPL1655 |
GTPL1656 |
DTXSID3046326 |
BDBM21130 |
AOB5676 |
WDA74475 |
ZINC2517042 |
Tox21_112026 |
MFCD05664586 |
AKOS037643567 |
Tox21_112026_1 |
NCGC00163179-02 |
NCGC00163179-03 |
AS-16910 |
BCP0726000202 |
1-Oxaspiro4.5decane, benzeneacetamide deriv. |
U069593 |
Q7862883 |
N-methyl-2-phenyl-N-(7-(pyrrolidin-1-yl)-1-oxaspiro4.5decan-8-yl)acetamide |
N-Methyl-N-(5R)-7alpha-(1-pyrrolidinyl)-1-oxaspiro4.5decan-8beta-ylbenzeneacetamide |
Benzeneacetamide, N-methyl-N-(5R,7S,8S)-7-(1-pyrrolidinyl)-1-oxaspiro4.5dec-8-yl- (9CI) |
Benzeneacetamide, N-methyl-N-7-(1-pyrrolidinyl)-1-oxaspiro4.5dec-8-yl-, 5R-(5alpha,7alpha,8beta)- |
Experimental Data
U-69593
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -13 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
U-69593
Statistics Data
U-69593
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -13 | 1 | 1 |
Statistics Data Visualization
U-69593
