Compound Summary
Compound Information
N6-Methyladenosine
Compound Name: | N6-Methyladenosine |
Compound CID: | 102175 |
Synonyms: | N6-Methyladenosine N-Methyladenosine 1867-73-8 6-Methyladenosine N(6)-Methyladenosine More... |
Iupac Name: | (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(methylamino)purin-9-yl]oxolane-3,4-diol |
InChI: | InChI=1S/C11H15N5O4/c1-12-9-6-10(14-3-13-9)16(4-15-6)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11,17-19H,2H2,1H3,(H,12,13,14)/t5-,7-,8-,11-/m1/s1 |
InChIKey: | VQAYFKKCNSOZKM-IOSLPCCCSA-N |
Canonical Smiles: | CNC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)O |
Isomeric Smiles: | CNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O |
Molecular Weight: | 281.27 |
Molecular Formula: | C11H15N5O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
N6-Methyladenosine
Molecular Weight: | 281.27 |
Molecular Formula: | C11H15N5O4 |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 8 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 20 |
Complexity: | 349 |
Synonyms
N6-Methyladenosine
| N6-Methyladenosine | N6-Methyladenosine |
|---|---|
N6-Methyladenosine |
N-Methyladenosine |
1867-73-8 |
6-Methyladenosine |
N(6)-Methyladenosine |
6-Methylaminopurinosine |
6-Methylaminopurine riboside |
6-Methylaminopurine D-riboside |
N6-methyladenosine (m6A) |
6-Methylaminopurine ribonucleoside |
(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-3,4-diol |
UNII-CLE6G00625 |
M6A |
CHEBI:21891 |
(N-6)-Methyladenosine |
N(6)-monomethyladenosine |
CHEMBL383144 |
CLE6G00625 |
NSC-29409 |
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-6-(methylamino)purin-9-yloxolane-3,4-diol |
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-6-(methylamino)-9H-purin-9-yloxolane-3,4-diol |
(2R,3S,4R,5R)-2-Hydroxymethyl-5-(6-methylamino-purin-9-yl)-tetrahydro-furan-3,4-diol |
NSC627045 |
4rdn |
6MD |
Prestwick_343 |
N6 -methyladenosine |
Prestwick0_000338 |
Prestwick1_000338 |
Prestwick2_000338 |
Prestwick3_000338 |
Epitope ID:140951 |
SCHEMBL40634 |
BSPBio_000375 |
MLS002153780 |
SPBio_002296 |
BPBio1_000413 |
DTXSID6020858 |
HMS1569C17 |
HMS2096C17 |
HMS2234N05 |
HMS3713C17 |
HY-N0086 |
ZINC4245632 |
2575AH |
BDBM50163023 |
MFCD00005739 |
PDSP1_001030 |
PDSP2_001014 |
s3190 |
Adenosine, N-methyl- (8CI)(9CI) |
AKOS024260287 |
CCG-220338 |
CS-3285 |
GS-6701 |
NCGC00162241-01 |
NCGC00162241-02 |
NCGC00162241-04 |
NCGC00162241-09 |
SMR001233164 |
6-methylamino-9-beta-D-ribofuranosyl-Purine |
ST50412061 |
SW196617-3 |
6-methylamino-9-beta-delta-ribofuranosyl-Purine |
F12902 |
Purine, 6-methylamino-9-beta-D-ribofuranosyl- |
J-700317 |
Q6951996 |
BRD-K81807412-001-03-1 |
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-6-(methylamino)purin-9-yltetrahydrofuran-3,4-diol |
(4S,2R,3R,5R)-5-(hydroxymethyl)-2-6-(methylamino)purin-9-yloxolane-3,4-diol |
Experimental Data
N6-Methyladenosine
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 3 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
N6-Methyladenosine
Statistics Data
N6-Methyladenosine
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 3 | 1 | 1 |
Statistics Data Visualization
N6-Methyladenosine
