Compound Summary
Compound Information
Indirubin
Compound Name: | Indirubin |
Compound CID: | 10177 |
Synonyms: | Indirubin 479-41-4 Indigo Red Couroupitine B Indigopurpurin More... |
Iupac Name: | 2-(2-hydroxy-1H-indol-3-yl)indol-3-one |
InChI: | InChI=1S/C16H10N2O2/c19-15-10-6-2-4-8-12(10)17-14(15)13-9-5-1-3-7-11(9)18-16(13)20/h1-8,18,20H |
InChIKey: | JNLNPCNGMHKCKO-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC=C2C(=C1)C(=C(N2)O)C3=NC4=CC=CC=C4C3=O |
Isomeric Smiles: | C1=CC=C2C(=C1)C(=C(N2)O)C3=NC4=CC=CC=C4C3=O |
Molecular Weight: | 262.26 |
Molecular Formula: | C16H10N2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Indirubin
Molecular Weight: | 262.26 |
Molecular Formula: | C16H10N2O2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 20 |
Complexity: | 448 |
Synonyms
Indirubin
| Indirubin | Indirubin |
|---|---|
Indirubin |
479-41-4 |
Indigo Red |
Couroupitine B |
Indigopurpurin |
906748-38-7 |
(Z)-2,3-biindolinylidene-2,3-dione |
UNII-V86L8P74GI |
NSC 105327 |
NSC-105327 |
3-(3-oxo-1H-indol-2-ylidene)-1H-indol-2-one |
(E)-2,3-biindolinylidene-2,3-dione |
C.I. 73200 |
397242-72-7 |
UNII-1LXW6D3W2Z |
1LXW6D3W2Z |
2H-Indol-2-one, 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro- |
(Z)-2,3 inverted exclamation mark -Biindolinylidene-2 inverted exclamation mark ,3-dione |
V86L8P74GI |
2-(2-hydroxy-1H-indol-3-yl)indol-3-one |
MFCD00956441 |
2,3-Biindolinylidene-2,3-dione |
C.I. 75790 |
MFCD00221745 |
3-(1,3-dihydro-3-oxo-2h-indol-2-ylidene)-1,3-dihydro-2h-indol-2-one |
SMR000466311 |
BRN 0088279 |
Isoindirubin |
Isoindirubine |
Isoindogotin |
Indirubin MI |
Indirubin,(S) |
Indirubin- Bio-X |
INDARUBICIN |
CPD000466311 |
Indirubin derivative, 1 |
BiomolKI_000069 |
EM-A05-INDIRUBIN |
.DELTA.2,3-dione |
Indirubin 3E-form MI |
BiomolKI2_000073 |
(3Z)-3-(3-oxoindolin-2-ylidene)indolin-2-one |
(delta(sup 2,3)-BIINDOLINE)-2,3-DIONE |
SCHEMBL27678 |
BMK1-G9 |
BSPBio_001110 |
KBioGR_000450 |
KBioSS_000450 |
5-24-08-00507 (Beilstein Handbook Reference) |
MLS000759416 |
MLS001424211 |
MLS002473308 |
MLS006010732 |
CHEMBL35349 |
BDBM7392 |
CHEMBL259664 |
SCHEMBL9899338 |
(3E)-3-(3-oxo-1H-indol-2-ylidene)-1H-indol-2-one |
CHEMBL1276127 |
CHEMBL3185783 |
CHEBI:92322 |
cid_5318433 |
KBio2_000450 |
KBio2_003018 |
KBio2_005586 |
KBio3_000839 |
KBio3_000840 |
EX-A347 |
Bio2_000395 |
Bio2_000875 |
HMS1362H11 |
HMS1792H11 |
HMS1990H11 |
HMS2051H20 |
HMS2234G06 |
HMS3369O15 |
HMS3393H20 |
HMS3403H11 |
HMS3656O13 |
ACT03264 |
AMY39890 |
BCP28869 |
HY-N0117 |
AC1180 |
BDBM50023867 |
BDBM50349806 |
FD9058 |
NSC105327 |
s2386 |
ZINC18825333 |
2H-Indol-2-one,3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro- |
3-(1,3-dihydro-3-oxo-2h-indol-2-ylidene)-1,3-dihydro-2h-indol-2-on |
AKOS015895136 |
AKOS028108775 |
AKOS032455876 |
ZINC100015416 |
AC-8003 |
BCP9000788 |
CCG-100673 |
CCG-101058 |
CCG-267073 |
CS-3682 |
DB12379 |
NC00308 |
SB64698 |
IDI1_002150 |
(2Z)-Indirubin, >=98% (HPLC) |
NCGC00163356-01 |
NCGC00163356-02 |
NCGC00163356-03 |
NCGC00163356-04 |
NCGC00179302-02 |
AC-29931 |
BI164578 |
CS-12423 |
LS-14462 |
SMR004701694 |
SY058396 |
3-(3-oxoindolin-2-ylidene)indolin-2-one |
3-(3-indolinone-2-ylidene)-indolin-2-one |
AB0020115 |
UNM-0000305766 |
FT-0627199 |
I0868 |
SW197688-2 |
V0881 |
(delta2,3-Biindoline)-2,3-dione (8CI) |
(E)-2,3-BIINDOLINYLIDENE-2,3-DIONE |
AB00639939-06 |
2-(2-oxo-1H-indol-3-ylidene)-1H-indol-3-one |
479I414 |
A827403 |
A922429 |
SR-01000759396 |
Q-100514 |
Q1661452 |
SR-01000759396-5 |
BRD-K17894950-001-03-6 |
BRD-K17894950-001-04-4 |
C.I.73200;Couroupitine B;Indigo red;Indigopurpurin |
Q27164070 |
3-(3-oxidanylidene-1H-indol-2-ylidene)-1H-indol-2-one |
2H-Indol-2-one,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro- |
(3E)-3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one |
(3E)-3-(3-Oxo-1,3-dihydro-2H-indol-2-ylidene)-1,3-dihydro-2H-indo l-2-one |
(3Z)-3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one |
2-(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene-2,3-dihydro-1H-indol-3-one |
2H-Indol-2-one, 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro- (9CI) |
2H-Indol-2-one, 3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-, (3E)- |
Indigo Red|||Couroupitine B|||(3E)-3-(3-Oxo-1H-indol-2-ylidene)-1H-indol-2-one |
Experimental Data
Indirubin
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 3 | mM | 8.2 | S | Oregon-R | 22363408 | Active |
Experimental Data Visualization
Indirubin
Statistics Data
Indirubin
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | 8.2 | 1 | 1 |
Statistics Data Visualization
Indirubin
