Compound Summary
Compound Information
LOBELINE HYDROCHLORIDE
Compound Name: | LOBELINE HYDROCHLORIDE |
Compound CID: | 101615 |
Synonyms: | LOBELINE HYDROCHLORIDE Lobeline HCl 134-63-4 alpha-Lobeline hydrochloride (-)-Lobeline hydrochloride More... |
Iupac Name: | 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl]-1-phenylethanone;hydrochloride |
InChI: | InChI=1S/C22H27NO2.ClH/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18;/h2-7,9-12,19-21,24H,8,13-16H2,1H3;1H/t19-,20+,21-;/m0./s1 |
InChIKey: | MKMYPTLXLWOUSO-NFQNBQCWSA-N |
Canonical Smiles: | CN1C(CCCC1CC(=O)C2=CC=CC=C2)CC(C3=CC=CC=C3)O.Cl |
Isomeric Smiles: | CN1[C@@H](CCC[C@@H]1CC(=O)C2=CC=CC=C2)C[C@@H](C3=CC=CC=C3)O.Cl |
Molecular Weight: | 373.9 |
Molecular Formula: | C22H28ClNO2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
LOBELINE HYDROCHLORIDE
Molecular Weight: | 373.9 |
Molecular Formula: | C22H28ClNO2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 26 |
Complexity: | 412 |
Synonyms
LOBELINE HYDROCHLORIDE
| LOBELINE HYDROCHLORIDE | LOBELINE HYDROCHLORIDE |
|---|---|
LOBELINE HYDROCHLORIDE |
Lobeline HCl |
134-63-4 |
alpha-Lobeline hydrochloride |
(-)-Lobeline hydrochloride |
Lobeline (hydrochloride) |
UNII-96J834CB88 |
L-Lobeline hydrochloride |
Zoolobelin |
Lobeline hydrochloride JAN |
MLS000069392 |
MFCD00082455 |
Lobron |
96J834CB88 |
SMR000058465 |
Alpha-Lobeline HCl |
2-(2R,6S)-6-(2S)-2-hydroxy-2-phenylethyl-1-methylpiperidin-2-yl-1-phenylethanone hydrochloride |
Lobeline hydrochloride (JAN) |
2-((2R,6S)-6-((S)-2-Hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethan-1-one hydrochloride |
2-(2R,6S)-6-(2S)-2-hydroxy-2-phenylethyl-1-methylpiperidin-2-yl-1-phenylethanone;hydrochloride |
Lobelin Hydrochlorde |
Lobelin hydrochloride |
Lobelini hydrochloridum |
Lobelinum hydrochloricum |
SR-01000000002 |
Lobeline alpha (-) hydrochoride |
SR-01000075960 |
(-)-alpha-Lobeline hydrochloride |
EINECS 205-150-2 |
a-Lobeline hydrochloride |
Opera_ID_410 |
MLS000758290 |
MLS001148112 |
MLS001424136 |
SCHEMBL467021 |
CHEMBL1257005 |
DTXSID10928382 |
HMS1569F12 |
(-)-Lobeline hydrochloride, 98% |
ACT06730 |
EX-A1345 |
HY-B0979 |
Tox21_500698 |
s3972 |
AKOS024282588 |
AM62794 |
CCG-101032 |
CS-4469 |
LP00698 |
NC00282 |
Acetophenone, 2-(6-(beta-hydroxyphenethyl)-1-methyl-2-piperidyl)-, hydrochloride, (-)- |
NCGC00094052-01 |
NCGC00261383-01 |
AS-48029 |
EU-0100698 |
D02202 |
F17567 |
L 4376 |
SR-01000000002-2 |
SR-01000000002-5 |
SR-01000075960-1 |
Q27271904 |
Lobeline hydrochloride, European Pharmacopoeia (EP) Reference Standard |
2-(2R,6S)-6-(2S)-2-Hydroxyphenethyl)-1-methyl-2-piperidinylacetophenone hydrochloride |
2-((2R,6S)-6-((S)-2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone hydrochloride |
2-(2S,6R)-6-(2S)-2-Hydroxy-2-phenylethyl-1-methylpiperidin-2-yl-1-phenylethanone;hydrochloride |
Ethanone, 2-((2R,6S)-6-((2S)-2-hydroxy-2-phenylethyl)-1-methyl-2-piperidinyl)-1-phenyl-, hydrochloride |
Ethanone, 2-(6-(2-hydroxy-2-phenylethyl)-1-methyl-2-piperidinyl)-1-phenyl-, hydrochloride, (2R-(2alpha,6alpha(S*))- |
Ethanone, 2-(2R,6S)-6-(2S)-2-hydroxy-2-phenylethyl-1-methyl-2-piperidinyl-1-phenyl-, hydrochloride (1:1) |
Experimental Data
LOBELINE HYDROCHLORIDE
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -10 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
LOBELINE HYDROCHLORIDE
Statistics Data
LOBELINE HYDROCHLORIDE
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -10 | 1 | 1 |
Statistics Data Visualization
LOBELINE HYDROCHLORIDE
