Compound Summary
Compound Information
Naphthazarin
Compound Name: | Naphthazarin |
Compound CID: | 10141 |
Synonyms: | Naphthazarin 5,8-Dihydroxy-1,4-naphthoquinone 475-38-7 5,8-dihydroxynaphthalene-1,4-dione Naphthazarine More... |
Iupac Name: | 5,8-dihydroxynaphthalene-1,4-dione |
InChI: | InChI=1S/C10H6O4/c11-5-1-2-6(12)10-8(14)4-3-7(13)9(5)10/h1-4,11-12H |
InChIKey: | RQNVIKXOOKXAJQ-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC(=C2C(=O)C=CC(=O)C2=C1O)O |
Isomeric Smiles: | C1=CC(=C2C(=O)C=CC(=O)C2=C1O)O |
Molecular Weight: | 190.15 |
Molecular Formula: | C10H6O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Naphthazarin
Molecular Weight: | 190.15 |
Molecular Formula: | C10H6O4 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 0 |
Heavy Atom Count: | 14 |
Complexity: | 277 |
Synonyms
Naphthazarin
| Naphthazarin | Naphthazarin |
|---|---|
Naphthazarin |
5,8-Dihydroxy-1,4-naphthoquinone |
475-38-7 |
5,8-dihydroxynaphthalene-1,4-dione |
Naphthazarine |
Naphthazarone |
5,8-Dihydroxynaphthoquinone |
5,8-Dihydroxy-1,4-naphthalenedione |
NAPHTHAZALIN |
5,8-Dihydroxy-1,4-naphthosemiquinone |
5,8-Dihydroxy-1,4naphthoquinone |
UNII-S9IX5I5C0K |
S9IX5I5C0K |
CHEMBL274056 |
1,4-NAPHTHOQUINONE, 5,8-DIHYDROXY- |
CHEBI:28849 |
NSC26647 |
NSC344555 |
CCRIS 6670 |
Dihydroxynaphthoquinone |
EINECS 207-495-4 |
NAPTHAZARIN NPHZ |
5,4-naphthosemiquinone |
1, 5,8-dihydroxy- |
ACMC-209k9r |
5,8-Dihydroxynaphthaquinone |
SCHEMBL149279 |
NQ-2 |
SCHEMBL10866768 |
DTXSID00197161 |
ZINC901191 |
1,5-dihydroxy-4,8-naphthoquinone |
HY-N7526 |
4,8-Dihydroxy-1,5-naphthalenedione |
BDBM50060898 |
MFCD00001685 |
NSC-26647 |
SBB068464 |
AKOS015914982 |
NSC-344555 |
AS-76136 |
NCI60_002143 |
S310 |
DB-051459 |
CS-0132365 |
D2070 |
FT-0619861 |
ST50827776 |
1,4-Naphthalenedione, 5,8-dihydroxy- (9CI) |
10.14272/RQNVIKXOOKXAJQ-UHFFFAOYSA-N |
T70948 |
10.14272/RQNVIKXOOKXAJQ-UHFFFAOYSA-N.1 |
475D387 |
AE-641/01108012 |
doi:10.14272/RQNVIKXOOKXAJQ-UHFFFAOYSA-N |
5,8-Dihydroxy-1,4-naphthoquinone, technical grade |
doi:10.14272/RQNVIKXOOKXAJQ-UHFFFAOYSA-N.1 |
Q4639550 |
W-109038 |
Experimental Data
Naphthazarin
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 200 | umol/L | 22.3 | 24.2 | 0.09 | 26.5 | 30.3 | 0.14 | S | N2 | 21765926 | Active | |
| Caenorhabditis elegans | 100 | umol/L | 23.5 | 25.4 | 0.08 | 29.2 | 31.2 | 0.07 | S | N2 | 21765926 | Active | |
| Caenorhabditis elegans | 50 | umol/L | 22.3 | 22.8 | 0.02 | 26.5 | 26.4 | 0 | NS | N2 | 21765926 | Inactive | |
| Caenorhabditis elegans | 500 | umol/L | 22.3 | 27.3 | 0.22 | 26.5 | 33.1 | 0.25 | S | N2 | 21765926 | Active | |
| Caenorhabditis elegans | 100 | umol/L | 21.2 | 23.5 | 0.11 | 29.2 | 32.8 | 0.12 | S | N2 | 21765926 | Active | |
| Caenorhabditis elegans | 200 | umol/L | 21.2 | 25.3 | 0.19 | 29.2 | 33.8 | 0.16 | S | N2 | 21765926 | Active | |
| Caenorhabditis elegans | 100 | umol/L | 22.3 | 24.5 | 0.1 | 26.5 | 29.6 | 0.12 | S | N2 | 21765926 | Active | |
| Caenorhabditis elegans | 500 | umol/L | 21.2 | 23.1 | 0.09 | 29.2 | 30.4 | 0.04 | S | N2 | 21765926 | Active | |
| Caenorhabditis elegans | 500 | umol/L | 23.5 | 26.8 | 0.14 | 29.2 | 31.6 | 0.08 | S | N2 | 21765926 | Active | |
| Caenorhabditis elegans | 200 | umol/L | 23.5 | 25.9 | 0.1 | 29.2 | 31.4 | 0.08 | S | N2 | 21765926 | Active |
Experimental Data Visualization
Naphthazarin
Statistics Data
Naphthazarin
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0.22 | 0.25 | 1 | 10 |
Statistics Data Visualization
Naphthazarin
