Compound Summary
Compound Information
L-765,314
Compound Name: | L-765,314 |
Compound CID: | 10098248 |
Synonyms: | L-765,314 NCGC00094440-01 Lopac0_001186 SCHEMBL8704241 CHEMBL1322702 More... |
Iupac Name: | benzyl 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2-(tert-butylcarbamoyl)piperazine-1-carboxylate |
InChI: | InChI=1S/C27H34N6O5/c1-27(2,3)31-24(34)20-15-32(11-12-33(20)26(35)38-16-17-9-7-6-8-10-17)25-29-19-14-22(37-5)21(36-4)13-18(19)23(28)30-25/h6-10,13-14,20H,11-12,15-16H2,1-5H3,(H,31,34)(H2,28,29,30) |
InChIKey: | CGWOIDCAGBKOQL-UHFFFAOYSA-N |
Canonical Smiles: | CC(C)(C)NC(=O)C1CN(CCN1C(=O)OCC2=CC=CC=C2)C3=NC4=CC(=C(C=C4C(=N3)N)OC)OC |
Isomeric Smiles: | CC(C)(C)NC(=O)C1CN(CCN1C(=O)OCC2=CC=CC=C2)C3=NC4=CC(=C(C=C4C(=N3)N)OC)OC |
Molecular Weight: | 522.6 |
Molecular Formula: | C27H34N6O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
L-765,314
Molecular Weight: | 522.6 |
Molecular Formula: | C27H34N6O5 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 9 |
Rotatable Bond Count: | 8 |
Heavy Atom Count: | 38 |
Complexity: | 803 |
Synonyms
L-765,314
| L-765,314 | L-765,314 |
|---|---|
L-765,314 |
NCGC00094440-01 |
Lopac0_001186 |
SCHEMBL8704241 |
CHEMBL1322702 |
BCP30192 |
CCG-205260 |
LP01186 |
SDCCGSBI-0051153.P002 |
NCGC00015604-02 |
NCGC00015604-03 |
NCGC00015604-04 |
NCGC00094440-02 |
EU-0101186 |
L 3040 |
L016366 |
SR-01000076155 |
SR-01000076155-1 |
L-765,314; L 765314; L765314 |
(2S)-4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-2-(1,1-Dimethylethyl)aminocarbonyl-1-piperazinecarboxylic acid, phenylmethyl ester |
Experimental Data
L-765,314
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 3 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
L-765,314
Statistics Data
L-765,314
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 3 | 1 | 1 |
Statistics Data Visualization
L-765,314
