Compound Summary
Compound Information
Oglufanide
Compound Name: | Oglufanide |
Compound CID: | 100094 |
Synonyms: | Oglufanide H-Glu-Trp-OH 38101-59-6 Glu-trp Thymogen More... |
Iupac Name: | (4S)-4-amino-5-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-oxopentanoic acid |
InChI: | InChI=1S/C16H19N3O5/c17-11(5-6-14(20)21)15(22)19-13(16(23)24)7-9-8-18-12-4-2-1-3-10(9)12/h1-4,8,11,13,18H,5-7,17H2,(H,19,22)(H,20,21)(H,23,24)/t11-,13-/m0/s1 |
InChIKey: | LLEUXCDZPQOJMY-AAEUAGOBSA-N |
Canonical Smiles: | C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)NC(=O)C(CCC(=O)O)N |
Isomeric Smiles: | C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)O)NC(=O)[C@H](CCC(=O)O)N |
Molecular Weight: | 333.34 |
Molecular Formula: | C16H19N3O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Oglufanide
Molecular Weight: | 333.34 |
Molecular Formula: | C16H19N3O5 |
Hydrogen Bond Donor Count: | 5 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 8 |
Heavy Atom Count: | 24 |
Complexity: | 484 |
Synonyms
Oglufanide
| Oglufanide | Oglufanide |
|---|---|
Oglufanide |
H-Glu-Trp-OH |
38101-59-6 |
Glu-trp |
Thymogen |
L-glutamyl-L-tryptophan |
Glutamyltryptophan |
alpha-Glutamyltryptophan |
L-Glu-L-Trp |
L-alpha-Glutamyl-L-tryptophan |
Oglufanide disodium |
alpha-Glu-Trp |
UNII-4RHY598T5U |
IM 862 |
L-alpha-Glu-L-Trp |
122933-59-9 |
IM862 |
4RHY598T5U |
CHEBI:73512 |
Timogen |
Glutamyl tryptophan |
Oglufanide INN |
(S)-4-Amino-5-(((S)-1-carboxy-2-(1H-indol-3-yl)ethyl)amino)-5-oxopentanoic acid |
IM 862 dipeptide |
NSC 334073 |
CCRIS 8677 |
EW dipeptide |
NSC334073 |
L-Tryptophan, L-alpha-glutamyl- |
E-W Dipeptide |
NSC-334073 |
glutamyl-tryptophan |
L-Tryptophan, N-L-alpha-glutamyl- |
Thymogen(Oglufanide) |
Glutamate Tryptophan dipeptide |
Glutamate-Tryptophan dipeptide |
N-(2-Amino-4-carboxy-1-hydroxybutylidene)tryptophan |
SCHEMBL1898073 |
CHEMBL2111029 |
DTXSID10924324 |
(4S)-4-amino-5-(1S)-1-carboxy-2-(1H-indol-3-yl)ethylamino-5-oxopentanoic acid |
BCP13098 |
ZINC1576166 |
MFCD00037953 |
AKOS026751470 |
CS-5654 |
DB05779 |
L-Tryptophan, L-a-glutamyl-;Oglufanide |
AS-49440 |
HY-13718 |
FT-0771477 |
I10346 |
A904491 |
Q4457491 |
4-Amino-5-1-carboxy-2-(1H-indol-3-yl)ethylamino-5-oxopentanoic acid |
(4S)-4-N-((1S)-1-carboxy-2-indol-3-ylethyl)carbamoyl-4-aminobutanoic acid |
(S)-4-amino-5-((S)-1-carboxy-2-(1H-indol-3-yl)ethylamino)-5-oxopentanoic acid |
Experimental Data
Oglufanide
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rattus norvegicus | 5 | ug | 773 | 789 | 0.02 | 965 | 1104 | 0.14 | S | FEMALES | 11707921 | Active |
Experimental Data Visualization
Oglufanide
Statistics Data
Oglufanide
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Rattus norvegicus | 0.02 | 0.14 | 1 | 1 |
Statistics Data Visualization
Oglufanide
